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by Serý, O. et al.Laboratory of Neurobiology and Molecular Psychiatry, Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech RepublicOur observations suggest that the C677T...

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by Wang, H. et al.1 Department of Pharmacy, Qilu Hospital, Shandong University, Jinan, ChinaMethylenetetrahydrofolate Reductase Polymorphism C677T Is a Protective Factor for Pediatric Acute...

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by Chellat, D. et al.Faculty of Natural and Life Sciences, Department of Animal Biology, Laboratory of Biology and Molecular Genetics, University Mentouri Constantine, AlgeriaThe data suggest that the...

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by Yan, L. et al.State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, ChinaAssociation of the Maternal MTHFR C677T Polymorphism with...

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by Yang, L. et al.Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, ChinaImpact of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on methotrexate-induced toxicities...

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by Sheng, X. et al.Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, Zhengzhou 450001, China We used crude odds ratios (ORs) with 95 % confidence intervals...

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by Huo, Y. et al.Department of Ophthalmology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, ChinaAssociation between MTHFR C677T polymorphism and primary...

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by Tu, Y.L. et al.Department of Hepatobiliary Surgery, the First Affiliated Hostpial of PLA General Hospital, Beijing, China E-mail :This meta-analysis indicated that MTHFR polymorphisms (C667T and...

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by El-Baz, R. et al.1Genetics Unit, Mansoura University, EgyptCases with diabetic nephropathy had a significantly higher frequency of the MTHFR 677 TT, 677 CT, ACE DD mutant genotypes compared with...

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by Rotondo, J.C. et al.Department of Morphology and Embryology, University of Ferrara, Ferrara 44121, Italy WHAT IS KNOWN ALREADY: Modifications to the MTHFR gene such as polymorphisms and promoter...

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by Xia, X.P. et al.1] Department of Gynecology and Obstetrics, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, ChinaMeta-analysis of the methylenetetrahydrofolate reductase...

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by Xu, F. et al.Department of Ophthalmology, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi, People's Republic of China; Guangxi Medical University, ChinaWe found that POAG is...

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by Poursadegh Zonouzi, A. et al.Department of Cellular and Molecular Biology, Faculty of Sciences, Azarbaijan University of Tarbiat Moallem, Tabriz, IranMethylenetetrahydrofolate Reductase C677T and...

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by Scher, A.I. et al.Lack of association between the MTHFR C677T variant and migraine with aura in an older population: could selective survival play a role?Cephalalgia. 2013; 5:308-15[See paper]

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by Chen, H. et al.MTHFR gene C677T polymorphism and type 2 diabetic nephropathy in Asian populations: a meta-analysis.Int. J. Clin. Exp. Med. 2015; 3:3662-70[See paper]

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by Jahanbin, A. et al.Analysis of MTHFR Gene C.677C>T and C.1298A>C Polymorphisms in Iranian Patients with Non-Syndromic Cleft Lip and Palate.Iran. J. Public Health. 2014; 6:821-7[See paper]

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by Li, D. et al.Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism, and risk of retinal vein occlusion: an updated meta-analysis.BMC. Ophthalmol. 2014; 147[See paper]

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by Suthandiram, S. et al.Polymorphisms in methylenetetrahydrofolate reductase gene and risk of non-Hodgkin lymphoma in a multi-ethnic population.J. Hum. Genet. 2014; 5:280-7[See paper]

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by Bradshaw, G. et al. No difference in methylation levels was detected between the case and control samples suggesting that although hypermethylation of MTHFR has been reported in tumour tissues,...

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by Singh, H.S. et al.A Study on MTHFR C677T Gene Polymorphism and Alcohol Dependence among Meiteis of Manipur, India.J. Biomark. 2014; 310241[See paper]

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by Qin, X. et al.Relationship of MTHFR gene 677C → T polymorphism, homocysteine, and estimated glomerular filtration rate levels with the risk of new-onset diabetes.Medicine. (Baltimore). 2015;...

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by Hu, C.Y. et al.Methylenetetrahydrofolate reductase (MTHFR) polymorphism susceptibility to schizophrenia and bipolar disorder: an updated meta-analysis.J. Neural. Transm. (Vienna). 2015;...

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by Chai, W. et al.Genetic association between methylenetetrahydrofolate reductase gene polymorphism and risk of osteonecrosis of the femoral head.Biomed. Res. Int. 2015; 196495[See paper]

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by Xuan, C. et al.Association between MTHFR polymorphisms and congenital heart disease: a meta-analysis based on 9,329 cases and 15,076 controls.Sci. Rep. 2014; 7311[See paper]

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by Li, S.Y. et al.Association between MTHFR C677T polymorphism and risk of acute lymphoblastic leukemia: a meta-analysis based on 51 case-control studies.Med. Sci. Monit. 2015; 740-8[See paper]

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by Liu, N.B. et al. Overall, no significant association was found between MTHFR C677T polymorphism and LC risk when all studies in Chinese populations were pooled into this meta-analysis.Med. Sci....

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by Wang, Y. et al.The association of the MTHFR c.1625A>C genetic variant with the risk of congenital heart diseases in the Chinese.Genet. Test. Mol. Biomarkers. 2015; 1:44-7[See paper]

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by Roy Moulik, N. et al.MTHFR gene polymorphism in acute lymphoblastic leukemia among North Indian children: a case-control study and meta-analysis updated from 2011.J. Hum. Genet. 2014; 7:397-404[See...

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by Rai, V. et al. The pooled OR was estimated under five genetic models and significant association was found between maternal MTHFR 677C>T polymorphism and Down syndrome under four genetic models...

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by Petr, M. et al.Effect of the MTHFR 677C/T polymorphism on homocysteinemia in response to creatine supplementation: a case study.Physiol. Res. 2013; 6:721-9[See paper]

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by Pramukarso, D.T. et al.This study supports that the MTHFR 677T allele polymorphism is not associated with hyperhomocysteinemia as well as an increase in C-IMT in post ischemic stroke patients.Ann....

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by Wang, Y. et al.Genetic variations in MTHFR and gastric cardia adenocarcinoma susceptibility in the Chinese Han population.Int. J. Clin. Exp. Med. 2015; 10:18936-44[See paper]

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by Li, Z. et al. After adjusting for age, gender, smoking, hypertension, hyperlipidemia, diabetes and MTHFR genotype for plasma Hcy levels, multifactor logistic regression analysis showed (OR=1.025,...

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by Varzari, A. et al.Polymorphisms of glutathione S-transferase and methylenetetrahydrofolate reductase genes in Moldavian patients with ulcerative colitis: Genotype-phenotype correlation.Meta. Gene....

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by Pei, J.S. et al.Our results indicated that the MTHFR C677T T allele was a protective biomarker for childhood ALL in Taiwan, and the association was more significant in male patients and in patients...

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by Zhu, Q. et al.Methylenetetrahydrofolate reductase polymorphisms at 3'-untranslated region are associated with susceptibility to preterm birth.Transl. Pediatr. 2015; 1:57-62[See paper]

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by Di Renzo, L. et al.C677T gene polymorphism of MTHFR and metabolic syndrome: response to dietary intervention.J. Transl. Med. 2014; 329[See paper]

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by Ma, L.M. et al. Overall, no significant association was found between MTHFR A1298C polymorphism and MM risk under all four genetic models (AC vs. AA, OR = 0.99, 95%CI = 0.82-1.20; CC vs. AA, OR =...

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by Joo Jeon, Y. et al. Of the potentially susceptible polymorphisms, MTHFR 2572C>A was associated with increased homocysteine and decreased folate levels in the plasma based on MTHFR 677CC.Sci....

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by Tara, S.S. et al.Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms in Male Partners of Recurrent Miscarriage Couples.J. Reprod. Infertil. 2015; 4:193-8[See paper]

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by Hou, J. et al.Two Mutations in the Caprine MTHFR 3'UTR Regulated by MicroRNAs Are Associated with Milk Production Traits.PLoS. ONE. 2015; 7:e0133015[See paper]

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by Shi, H. et al.Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease.PLoS. ONE. 2015; 6:e0128646[See paper]

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by Shu, J. et al.Association between the methylenetetrahydrofolate reductase gene C677T polymorphism and sudden sensorineural hearing loss: a meta-analysis.Eur. Arch. Otorhinolaryngol. 2015;...

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by Bellampalli, R. et al.Significance of 5,10-methylenetetrahydrofolate reductase gene variants in acute lymphoblastic leukemia in Indian population: an experimental, computational and...

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by Chen, Y. et al.This meta-analysis suggests that there is a significant association between MTHFR C677T polymorphism and thyroid cancer risk in Caucasians.Genet. Test. Mol. Biomarkers. 2014;...

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by Li, P. et al.Our findings provide empirical evidence that MTHFR genetic polymorphisms may decrease the toxicity of irinotecan-based chemotherapy and increase the clinical benefits for CRC...

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by El Hajj Chehadeh, S.W. et al.Relationship between MTHFR C677T and A1298C gene polymorphisms and complications of type 2 diabetes mellitus in an Emirati population.Meta. Gene. 2016; 70-5[See paper]

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by Chen, J. et al. Regardless of the genetic model tested we found no statistically significant association of MTHFR C677T polymorphism with preterm delivery or placental abruption.Acta. Obstet....

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by Hao, J. et al.Chinese Han people with TT/CT genotype of MTHFR gene may have increased the risk of developing breast cancer.J. Cancer. Res. Ther. 2015; C59-62[See paper]

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by Zhou, T.B. et al.Methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and diabetic nephropathy susceptibility in patients with type 2 diabetes mellitus.Ren. Fail. 2015; 8:1247-59[See...

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